Indianapolis Lutheran outscored Southwestern in each of the first three quarters to pull away for a season-opening 60-32 victory Thursday at Lutheran.
Hope King scored seven of her game-high 16 points in the second quarter when the Saints extended their lead to 32-11. Haley Doss added 10 points in the quarter.
Doss finished with 15 and Amelia Hughes reached double figures with 10 points.
Bryla Dunbar scored eight points in the fourth quarter to finish with a team-high 14 points for Southwestern. Harper McInerny had seven points.
Southwestern won the junior varsity game, 16-6.
The Spartans open their Mid-Hoosier Conference schedule Saturday at South Decatur.
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